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| 别名 | 银杏内酯B |
| 产品名 | Ginkgolide B (BN52021) |
| CAS号 | 15291-77-7 |
| 化学式 | C20H24O10 |
| 分子量 | 424.4 |
| 靶点 | PAFR拮抗剂 |
| 用途 | 仅供科学研究使用!不能用于人体及动物治疗 |
靶点及简介 ：
Ginkgolide B (BN-52021), an important active terpenoid from Ginkgo biloba leaves, is reported to increase cell viability and decrease cell apoptosis.IC50 value:Target:In vitro: Ginkgolide B (0.2 or 0.4 μg/ml) was added to the culture medium in vitro led to increases in cell viability and decreases in the number of hippocampal cells undergoing AAPH-induced apoptosis [1]. Ginkgolide B caused a dose-related protection against dysrhythmias; the antiarrhythmic effect of ginkgolide B was comparable to that of diltiazem and superior to the activity of metoprolol. Ginkgolide B can presumably prevent the re-entry mechanism involved in the development of ischemia-induced rhythm disturbances [2].In vivo: Oral administration of ginkgolide B (2 mg/kg/day, p.o.) caused a significant increase in cell viability and a highly significant decrease in the numbers of both spontaneously occurring and AAPH-induced apoptoses.
| 分子量 | 424.4 | 分子式 | C20H24O10 |
| CAS号 | 15291-77-7 | 目录号 | D801343 |
| Smiles | CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O | ||
| 储存条件(自签收日起) | |||
验证：
参考文献：
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.3563 mL | 11.7813 mL | 23.5627 mL |
| 5 mM | 0.4713 mL | 2.3563 mL | 4.7125 mL |
| 10 mM | 0.2356 mL | 1.1781 mL | 2.3563 mL |
关键词：Ginkgolide-B, BN-52021, Ginkgolide-B供应商, Metabolite/Endogenous Metabolite抑制剂, 购买Ginkgolide-B, Ginkgolide-B溶解度, Ginkgolide-B结构式
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液。
一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。（为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间)。
我们确保产品在保持试剂质量的条件下运输。收到产品后，请遵循产品数据表上的存储建议。
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